grindbioProtein Expression-as-a-Service
We combinatorially test all fusion partners, induction concentrations, and E. coli strains so you can cut the grind, saving money and time in your expression experiments.
Combinatorial Screening
We clone a gene into vectors with fusion proteins established to increase solubility and yield. The fusion partners are cloned in both N- and C-terminus orientations.
Real-Time Monitoring
We use bioreactors to monitor the concentration. No more guessing OD₆₀₀s for induction. Expression conditions are customized by inductor concentration and temperature.
GrindBio Features
Modular Bioreactor
Continuously measure optical density (OD) and temperature to maintain optimal conditions for protein expression.
Advanced Cloning System
Ligate your gene of interest into 12 different expression vectors with 10 fusion partners for enhanced solubility.
mRNA Abundance Analysis
Optimize expression by measuring metabolic stress and gene-of-interest mRNA levels in real-time.
High-Throughput Screening
Test thousands of biotic and abiotic conditions efficiently to find the best parameters for your protein.
Real-Time Readout
Gain immediate insights into protein solubility and the absence of inclusion bodies with our cutting-edge technology.
Comprehensive Data Reports
Receive detailed reports on protein concentration estimates in both soluble and insoluble fractions.